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06 Jun

Testosterone Cypionate is long acting formulation of testosterone which is indicated in the treatment of individuals who have absent or very low levels of the hormone. It is sometimes known as Depo testosterone. The testosterone is esterified and thus is quite long acting. It is only available in an injection form. The anabolic steroid is typically dissolved in sesame or cotton seed oil and injected into the buttock area. The drug is slowly released from the injection site for about 7-12 days.

The formulation comes as white milky powder and is insoluble in water but freely soluble in most organic solvents including vegetable oil.

Pharmacology

The body normally makes sex hormones like testosterone which is responsible for the normal growth and development of the secondary sexual features. This includes growth of the prostate, testes, penis, scrotum, body hair, vocal cord thickening, alterations in body fat and musculature. When testosterone deficiency occurs, the secondary sexual characteristics and body growth is always abnormal. Thus, one of the indications of testosterone therapy is in the treatment of individuals who lack testosterone or are infertile.

Indications for use

Testosterone Cypionate is used to treat conditions in made where there is a failure of testosterone to be secreted like:

  • primary failure of the testes to make the hormone
  • failure of the pituitary to release Gonadotropins

Bodybuilding

Testosterone and its analogues are widely used by athletes and bodybuilders. The steroid is taken principally to enhance the body and stimulate the psyche. Most bodybuilders who take this drug claim that it causes spontaneous bursts in energy associated with increased aggression. This feature of the drug is used primarily by weight lifters and professional wrestlers. Many athletes also claim that the drug improves their ability to perform exercise at intense levels.

Testosterone has moderate anabolic properties but also is a powerful androgenic agent.

Because the drug is given by an injection, its effects on the body are not rapid. One may not see any effects for at least 3-4 weeks after starting the injections. Unlike the oral testosterone, the injected formulations last a longer in the body.

When taken for more than 4-6 weeks, it can increase body mass and protein anabolism. However, for the body to build muscle one also has to eat a diet rich in calories. Most bodybuilders also take a combination of other hormones at the same time. Because testosterone is converted to estrogen in the fatty tissues, there is always the chance of developing gynecomastia and water retention. To prevent this, most bodybuilders addArimidex or tamoxifen during the off cycle.

During testosterone injections, the natural body testosterone release is inhibited by feedback mechanism through inhibition of pituitary LH. At large doses, even spermatogenesis can be impaired. To allow for the hypothalamic-pituitary axis to recover, it is highly recommended that the drug be tapered off slowly over a period of a few weeks. Sudden discontinuation of the drug can lead to extreme fatigue, weight lossand susceptibility to fractures.

Contraindications

There are some individuals who should avoid testosterone like steroids because it can worsen the clinical condition. These conditions include:

  • those with allergy to the drug
  • males with breast cancer
  • males with prostate cancer
  • Women who are pregnant or breast feeding
  • Individuals who have liver, kidney or heart problems

Side Effects

When Testosterone Cypionate is injected at low doses, the side effects are rare. However, long term use is known to be associated with a varied number of side effects – all of which are reversible when the drug is stopped. For the female who decides to take testosterone, there are virilizing side effects which are not always reversible when the drug is stopped. Like all anabolic steroids, testosterone also has a number of side effects which includes:

  • nausea, vomiting
  • abdominal cramps, diarrhea
  • swelling
  • ncreased /decreased libido
  • headaches
  • acne, oily skin
  • mental change including anger, depression, insomnia
  • diaphoresis
  • loss of hair
  • gynecomastia

When taken by females, the drug definitely can cause virilizing effects like:

  • deepening of voice
  • hoarseness
  • excess hair growth
  • enlarged clitoris
  • irregular menstrual cycles

Testosterone Cypionate is converted into estrogen in the fatty tissues. The estrogen than leads to development of breast enlargement and water retention. This effect is typically seen after the steroid has been used for more than 4 weeks. The gynecomastia does reverse when the steroid is discontinued.

Over dose

Over dose with Testosterone Cypionate is very rare. The drug is usually administered as an injection. If excess dose is injected, there are no acute side effects but the individual may feel sick for a few weeks. Depending on the dose injected, a visit to the hospital or a physician’s office would not be a bad idea.

Dosage

In clinical medicine, Testosterone Cypionate is administered as an injection. The oily suspension is injected only into the muscles.Testosterone Cypionate is available in two strengths 100mg/ml and 200 mg/ml. It is only made for intramuscular injection. The drug can be injected into the buttock area once every 7-12 days. The majority of the Testosterone Cypionate is bound to protein and only 2% is free. The drug is supposed to be injected once a week, but there are some bodybuilders who do inject it every other day.

This is not recommended and can lead to the formation of abscess, sores and skin infections.

The injection site needs to be rotated if the injections are to be continued for a long time. The oily suspension should not be injected into the arms or the abdomen. The dose of Testosterone Cypionate ranges from 50mg-400mg/week, depending on the condition being treated. Bodybuilders tend to inject the higher amount of the drug- 200mg-400mg/week. The drug is then slowly absorbed into the blood stream over the next few days.

Control

Testosterone Cypionate is a controlled substance and classified under class 3 under the Controlled Substance Act. It is only available in the USA with a physician’s prescription. Possession, distribution or sell of this anabolic steroid is considered illegal.

Detection

Anytime an oily suspension of drug is used, the drug does tend to remain in the body for a long time. Testosterone Cypionate and its metabolites can be detected in the urine for as long as 2-3 weeks after the last injection. Because of this long duration in the body, most bodybuilders prefer to take the drug during the off season.

Availability

The majority of bodybuilders get their Testosterone Cypionate from the black market. In the USA the original pharmaceutical product is well controlled and not available for sale. Generic forms of the steroid have been made in Japan, Australia, Mexico, Spain, Brazil and Thailand is all available.

Most bodybuilders use between 200-600mg/week and a vial of 400mg in 2 ml can cost anywhere from $20-$40. this can easily amount to $200 per month depending on the dose.

However, like all things in cyberspace the purity and quality of the product is always in question. And fakes products are plentiful.

30 May

Blood doping is an unlawful method for enhancing athletic execution by falsely boosting the blood’s capacity to convey more oxygen to muscles.

As a rule, blood doping builds the measure of hemoglobin in the circulation system. Hemoglobin is an oxygen-conveying protein in the blood. So expanding hemoglobin permits higher measures of oxygen to reach and fuel a competitor’s muscles. This can enhance stamina and execution, especially in long-separate occasions, for example, running and cycling.

 

Blood doping is banned by the International Olympic Committee and different sports associations.

Sorts of Blood Doping

The three generally utilized sorts of blood doping are:

  • blood transfusions
  • infusions of erythropoietin (EPO)
  • infusions of manufactured oxygen transporters

Here are some more insights about each of these sorts of blood doping:

Blood transfusions. In ordinary medicinal practice, patients may experience blood transfusions to supplant blood lost because of harm or surgery. Transfusions additionally are given to patients who experience the ill effects of low red platelet numbers brought about by pallor, kidney disappointment, and different conditions or medicines.

Illegal blood transfusions are utilized by competitors to help execution. There are two sorts.

Autologous transfusion. This includes a transfusion of the competitor’s own blood, which is drawn and afterward put away for future utilization.

Homologous transfusion. In this sort of transfusion, competitors utilize the blood of another person with the same blood classification.

EPO infusions. EPO is a hormone created by the kidney. It manages the body’s generation of red blood cells.

In medical practice, EPO injections are given to stimulate the production of red blood cells. For example, a synthetic EPO can be used to treat patients with anemia related to chronic or end-stage kidney disease.

Athletes using EPO do so to encourage their bodies to produce higher than normal amounts of red blood cells to enhance performance.

Synthetic oxygen carriers. These are chemicals that have the ability to carry oxygen. Two examples are:

  • HBOCs (hemoglobin-based oxygen carriers)
  • PFCs (perfluorocarbons)

Synthetic oxygen carriers have a legitimate medical use as emergency therapy. It is used when a patient needs a blood transfusion but:

  • human blood is not available
  • there is a high risk of blood infection
  • there isn’t enough time to find the proper match of blood type

Athletes use synthetic oxygen carriers to achieve the same performance-enhancing effects of other types of blood doping: increased oxygen in the blood that helps fuel muscles.

21 May

One of the most effective routes to gaining strength is to take some kind of anabolic steroid. These supplements actually aid the body in building up muscle mass and endurance — and they can also bulk you up far beyond your expectations.

 

Anabolic steroids work because they masquerade as one of the body’s basic hormones: testosterone. Testosterone is, in fact, an anabolic steroid, and “anabolic-androgenic steroids” (the technical term for what most of us know as steroids) are just a synthetic version of this famous chemical. Anabolic refers to growth of muscles, and androgenic refers to male sex characteristics. We’ll call them anabolic steroids here, for accuracy’s sake.

How do anabolic steroids make you stronger?

In general, steroids are chemical compounds that share a common structure. There are several types of steroids; anabolic steroids are only one of several that have roles to play in your body.

When you take anabolic steroids, your body separates the supplement into molecules that can penetrate your cells. There, the steroid particles tie to structures called androgen receptors. This is where anabolic steroids truly take on the role of testosterone, because androgen receptors are formed particularly to tie with the body’s regular testosterone. Anabolic steroids, in any case, can also tie with the receptors.

Once this synthetic steroid is in place, the androgen receptor is activated. Depending on the type of cell the steroids are in, this activation can change how certain genes behave — especially the ones that control the changes that happen during puberty.

Steroids influence your ordinary digestion system in two fundamental ways, and together they bring about more mass and bulk. Once those androgen receptors are activated, a few cells expand their generation of proteins, which your body uses to construct more cells. This is the period of your metabolic cycle known as anabolism, where tiny molecules build up into more unpredictable ones and energy is stored. Anabolism is also when your body builds up muscles — so now you know why they’re called anabolic steroids. Amid anabolims, the cells in your skeletal muscles, or the capable muscles connected to your bones, start to reproduce and develop. Before long, you’re building up strength and agility.

But not all activated androgen receptors cause this reaction. Some inhibit hormones called glucocorticoids, another type of steroid. Inhibiting glucocorticoids speeds up the breakdown of complex molecules like proteins into smaller units like energy-giving amino acids. The entire breakdown process is called catabolism, and it’s the other half of your metabolic cycle.

By inihibiting glucocorticoids, anabolic steroids shorten the catabolic phase of metabolism. That means your muscles spend less time recovering between workouts, and you can do more with less rest. You can see how steroids might improve athletic performance.

Do they work?

One study showed that men who used steroids for 10 weeks gained 2 to 5 kilograms of lean body mass — muscle, in other words. They also reported a 5% to 20% increase in strength. Study participants gained more muscle mass in their chest, neck, shoulders and upper arms than in other areas. That’s not because they skipped leg day, but because the muscles in these areas have more androgen receptors in their cells. Not surprisingly, the participants improved more noticeably at bench-pressing than in other kinds of weight-lifting.

Use and Misuse

Doctors prescribe prescription based anabolic steroids to patients with diseases like cancer and AIDS, to help them regain body mass they have lost to their illnesses. Anabolic steroids are also prescribed to help treat certain hormone deficiencies. Our SDI Labs do not require a prescription and can be used to improve athletic performance, without worries about testing or breaking any rules.

Using steroids without a prescription can cause unpleasant side effects that go beyond drug charges and being labelled a cheater. Mostly, they’re linked to the androgenic effects of these supplements, or those effects related to male sex characteristics. Basically, your body thinks it’s going through puberty again. Activating the androgen receptors in your cells increases oil production in your sebaceous glands, which leads to acne.

That said, overuse of prescription anabolic steroids can also age you faster. It can lower sperm count and cause testicular atrophy, better known as shrinkage(which is oly temporary). Changing hormone levels can also lead to baldness in both men and women. It should start to become clear as to why SDI Labs are the right choice when it comes to adding mass and bulk, and as a bonus you have zero side effects.

It’s not inherently more dangerous to use steroids with a prescription. The problem is that people who use anabolic steroids to enhance athletic performance often have no medical training, and thus engage in riskier behaviours than people who take them legally. They often take higher doses, for longer periods of time. Many people who take anabolic steroids this way also do reckless things like improper steroid stacking and steroid cycling, which involves combining several types of anabolic steroids to make them more effective.

Anabolic steroids are one of those superpowers that comes with great responsibility. Bulking up with these supplements will actually turn you into a beast in the gym, when used correctly.